Pesticides - USP <561>m - GC/TQ

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Turnaround Time:

2 - 4 days

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Pesticides - USP <561>m - GC/TQ

Method Description

USP <561> pesticide testing using gas chromatography targets volatile and semi-volatile pesticide residues according to United States Pharmacopeia standards. This testing is required for pharmaceutical ingredients and dietary supplements to ensure safety and regulatory compliance. The method focuses on pesticides that are amenable to gas chromatographic separation and provides the sensitivity needed to meet USP limits.

Analyte List

Analyte NameLODLOQ
Parathion Ethyl + Paraoxon Ethyl1 ng/g2 ng/g
Fenitrothion1 ng/g2 ng/g
Tecnazene0.1 ng/g0.2 ng/g
Procymidone0.2 ng/g0.4 ng/g
Bromopropylate6 ng/g12 ng/g
Endrin0.1 ng/g0.2 ng/g
Methacriphos0.1 ng/g0.2 ng/g
Bromophos Ethyl0.1 ng/g0.2 ng/g
DDT (Sum of O,P-DDE, P,P-DDE, O,P-DDT, P,P-DDT, O,P-TDE, and P,P-TDE)2 ng/g4 ng/g
Methoxychlor0.1 ng/g0.2 ng/g
Quintozene (Sum of Quintozene, Pentachloroaniline, and Methyl-Pentachlorophenyl Sulfide)2 ng/g4 ng/g
Fenchlorophos (Sum of Fenchlorophos and Fenchlorophos-Oxon)0.2 ng/g0.4 ng/g
Mirex0.02 ng/g0.04 ng/g
Tetradifon0.6 ng/g1.2 ng/g
Hexachlorocyclohexane (Sum of Isomers Alpha-, Beta-, Delta-, and Epsilon-)0.6 ng/g1.2 ng/g
Bromophos Methyl0.1 ng/g0.2 ng/g
Endosulfan (Sum of Isomers and Sulphate)6 ng/g12 ng/g
Lindane (Gamma-Hexachlorocyclohexane)1.2 ng/g2.4 ng/g
Vinclozolin0.8 ng/g1.6 ng/g
Chlorthal-Dimethyl0.02 ng/g0.04 ng/g
Heptachlor (Sum of Heptachlor, Cis-Heptachlorepoxide, and Trans-Heptachlorepoxide)0.1 ng/g0.2 ng/g
Hexachlorobenzene0.2 ng/g0.4 ng/g
Fenvalerate3 ng/g6 ng/g
Chlordane (Sum of -Cis, -Trans, Oxychlordane)0.1 ng/g0.2 ng/g
S-4210.04 ng/g0.08 ng/g
Fluvalinate-Tau0.1 ng/g0.2 ng/g
Dicofol1 ng/g2 ng/g
Aldrin + Dieldrin0.1 ng/g0.2 ng/g
Pentachloroanisole0.02 ng/g0.04 ng/g
Chlorpyrifos Methyl0.2 ng/g0.4 ng/g
Parathion Methyl + Paraoxon Methyl0.4 ng/g0.8 ng/g

Technical Data Sheet

Method Name
USP 561 Pesticides Analysis in Articles of Botanical Origin by GC/TQ
Method Code
LAB-TM-039
Equipment Type
Gas Chromatography - Tandem Mass Spectrometry (GC-MS/MS)
Equipment Details
Method Reference
Reportable Unit
ppm (mg/kg)
Sample Size Requirements
500 grams
Available for
Food Products, Dietary Supplements, Botanicals (Raw Materials, Extracts, Finished Products), API (Isolates, Active Ingredients)
Additional Information
Modified Test Method does not include the following analytes: Bromide, inorganic (calculated as bromide ion) Chlorpyriphos-methyl Dichlofluanid Dithiocarbamates (as CS2) Parathion-methyl and Paraoxon-methyl (sum of)
Unavailable for
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